ATC-CODE: A04AB04 R06AE05 

CAS: 000569653
NAME: Meclizine
SYSTEMATIC NAME:
Meclozine
Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-((3-methylphenyl)methyl)-
Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)-

CLASSIFICATION CODE:
Anti-allergic agents
Antiemetics
Drug / Therapeutic Agent
Histamine H1 antagonists
Human Data
Reproductive Effect

FORMULA:
C25-H27-Cl-N2

MIXTURE:
SYNONYMS: (+-)-Meclizine
1-((4-Chlorophenyl)phenylmethyl)-4-((3-methylphenyl)methyl)piperazine
1-(p-Chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)piperazine
1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine
1-p-Chlorobenzhydryl-4-m-methylbenzylpiperazine
5-23-01-00235 (Beilstein Handbook Reference)
Ancolan
BRN 0332002
Bonadettes
Bonine
Calmonal
Chiclida
EINECS 209-323-3
HSDB 3113
Histamethine
Histamethizine
Histametizine
Histametizyne
Itinerol
Marex
Meclizine
Meclozina [INN-Spanish]
Meclozine
Meclozinum [INN-Latin]
Monamine
NSC 169189
Navicalm
Neo-istafene
Neo-suprimal
Neo-suprimel
Parachloramine
Peremesin
Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-((3-methylphenyl)methyl)-
Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)-
Postafene
Ravelon
Sabari
Sea-Legs
Siguran
Suprimal
Travelon
U.C.B. 5062
UCB 170
UCB 5062
Vibazine
Vomisseis
NUMBER OF ROTATABLE BONDS: 5

NUMBER OF CHIRAL CENTERS:
1

NUMBER OF HYDROGEN BOND ACCEPTORS:
2

NUMBER OF HYDROGEN BOND DONORS:
0

SUM OF PARTIAL CHARGES:
0.00

SUM OF FORMAL CHARGES:
0.00

MOLECULAR DENSITY:
1.39

SURFACE AREA:
319.13

POLARIZABILITY:
17599.16

DIPOLE MAGNITUDE:
0.91

DIPOLE-X:
-0.17

DIPOLE-Y:
0.34

DIPOLE-Z:
0.82

RADIUS OF GYRATION:
7.45

MOLECULAR WEIGHT:
390.19